October 2015

  • Distinct mechanisms underlie quiescence during two Caenorhabditis elegans sleep-like states
    Distinct mechanisms underlie quiescence during two Caenorhabditis elegans sleep-like states
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    Distinct mechanisms underlie quiescence during two Caenorhabditis elegans sleep-like states

    Electrophysiological recordings have enabled identification of physiologically distinct yet behaviorally similar states of mammalian sleep. In contrast, sleep in nonmammals has generally been identified behaviorally and therefore regarded as a physiologically uniform state characterized by quiescence of feeding and locomotion, reduced responsiveness, and rapid reversibility. The nematode Caenorhabditis elegans displays sleep-like quiescent behavior under two…