How genes might specify the complex structures found in higher organisms is a major unsolved problem of biology.
first sentence of Brenner, 1974
If I had an hour to solve a problem and my life depended on the solution, I would spend the first 55 minutes determining the proper question to ask… for once I know the proper question, I could solve the problem in less than five minutes.
Opening day. All you have to do is say the words and you feel the shutters thrown wide, the room air out, the light pour in. In baseball, no other day is so pure with possibility. No scores yet, no losses, no blame or disappointment. No hangover, at least until the game’s over.